Epigenetic Age Acceleration and Its Link to Healthy Longevity in Older Women

By Max Cerquetti április 07, 2023 | Alzheimer's Alzheimer’s disease anti-aging biological clocks Cellular Senescence chronological age cognition cognitive function Cognitive Health DNA methylation eAge epigenetic age epigenetic alterations Epigenetic Clock epigenetische Alter Epigenetische Uhr gene expression Genexpression genomic instability genomics hallmarks of aging healthy aging heart health Horvath clock Human longevity Kognitive Gesundheit live longer mental health metabolic health Zelluläre Seneszenz

IntroductionAs the world's population ages, understanding the factors that contribute to healthy aging becomes increasingly important. One area of research that has garnered attention is the study of epigenetic age acceleration (EAA). EAA refers to the difference between a person's biological age, as measured by specific changes in their DNA,...

Epigenetic Clocks as Age Predictors: Their History, Strengths, and Limitations

By Max Cerquetti szeptember 08, 2021 | chAge chronological age DNA methylation DNAm eAge epigenetic age Epigenetic Clock Horvath clock

We know only too well that old age is the main risk factor for cancer, cardiovascular disease, and neurodegeneration. Frustratingly, advances in aging research were delayed for many years due to the poor reliability of tools used in predicting the rate of patients’ biological aging. To better understand the aging...