Sugar's Dark Side: How Glycolysis Fuels Cancer Beyond the 'Two-Hit' Theory

By Max Cerquetti May 12, 2024 | BRCA2 Cancer Prevention Cancer Research Diet and Cancer Genetic Mutations Glycolysis Metabolic Disorders Methylglyoxal Oncology Oncology Innovations Tumor Suppression

01. The Paradigm of Tumor Suppression Knudson's "Two-Hit" Paradigm Explained Understanding the Original "Two-Hit" HypothesisIn 1971, Alfred Knudson proposed the groundbreaking "two-hit" hypothesis to explain the development of hereditary retinoblastoma, a rare form of childhood eye cancer. According to this hypothesis, two successive genetic "hits" or mutations were necessary to...

Unveiling FAXDC2: A Breakthrough in Cancer Research and Treatment

By Max Cerquetti February 05, 2024 | anti-aging Breakthrough Treatments Cancer Research Cancer Therapy Cellular Growth Cholesterol and Cancer Cholesterol Synthesis DNA Repair Drug Development Duke-NUS Discoveries FAXDC2 Enzyme Genomic Technologies Metabolic Pathways Metabolic Pathways in Cancer Molecular Biology Oncology Innovations Personalized Medicine Preventative Strategies Scientific Advancements Scientific Breakthrough Targeted Therapies Wnt Signaling Wnt Signaling Pathway

IntroductionReady for a deep dive into something truly revolutionary in the world of cancer research? Buckle up, because we're about to explore a game-changing discovery that's stirring up the medical community and bringing new hope to the fight against cancer. It's all about a little-known enzyme called FAXDC2, and trust...