How Much Sleep Is Exactly The Right Amount? New Research Pinpoints The Exact Number Of Hours

How Much Sleep Is Exactly The Right Amount? New Research Pinpoints The Exact Number Of Hours

Ah, sleep! When you get the right amount of it, you feel great. But if you don’t sleep too well for a night or two, or worse, lose a night of sleep entirely, you can barely function. You, like all other human beings, have had a lifetime of personal experience with sleep, and have directly experienced how much of an impact it can have on how you function, or don’t!

So it should come as no big surprise that sleep plays an absolutely fundamental role in the optimal functioning of your brain, and is critical for cognitive and emotional processing, as well as memory and psychological health. Sleep also protects your brain by actually clearing waste products from the neural tissue while you sleep.

Researchers have long known that changes in one of the characteristics of sleep, namely how many hours of sleep you get each night, known as sleep duration, is linked to several conditions, including cardiovascular and cerebrovascular (brain blood vessel) disease as well as dementia.


A Non-Linear Relationship

But here’s where things get interesting. The relationship between sleep duration and the onset of these diseases is not exactly straightforward. It turns out that both too little sleep (6.5 hours or less per night) or too much sleep (more than 9 hours) are both linked to an increased risk. Definitely not a case of “more is better!”

Past research has shown that for each hour of reduced sleep duration there was an increase of 0.59 percent in the volume of the ventricles in study participants who were 55 years of age or older. The brain’s ventricles are a communicating network of cavities located deep within the brain tissue and filled with cerebrospinal fluid. The expansion of these ventricles, as shown on MRI, has long been associated with the progression of Alzheimer's disease.

Shorter sleep duration is also related to changes in the structure of the brain’s white matter, the tissue in the brain that is composed of nerve fibres. This explains why so many patients with dementia have a decline in their motor function, and subsequently develop difficulty with walking, picking up objects and even feeding or dressing themselves. It seems that previous research studies looking at sleep duration and brain structure were all focused on linear relationships, and not the clearly non-linear relationship described above, where either too little or too much sleep were both detrimental.


A New Study

But now, a new study by researchers from China’s Fudan University and the UK’s University of Cambridge, published in April 2022 in the prestigious journal Nature Aging, aims to correct this by directly examining this non-linear relationship. The scientists took data from a database known as the UK Biobank. This database is a very large-scale repository of genetic and health information from UK participants, and is widely used as a research resource. The information contained in the database includes cognitive assessments, mental health questionnaires, brain imaging studies and in-depth genetic information.

The researchers looked at data from some 500,000 adults aged 38 to 73 years. The team’s educated guess (in scientific terms, their hypothesis) going into the study was that this same non-linear relationship between sleep duration and the development of dementia would also be true of the relationship between sleep duration and mental health, as well as between sleep duration, cognition, and the structure of the brain itself.

 

UK_BioBank-Data-brain-imaging_mental-health_cognitive-function_genomics_sleep-duration


The Results

The research showed a definite association between too little sleep as well as too much sleep, on poor performance on cognitive tasks, including memory and reaction time. Sleep duration also showed this same two-sided relationship with mental health symptoms, including symptoms of depression, anxiety, and even self-harm behaviours. Even changes in brain structure, as determined by imaging data, showed this same nonlinear association, particularly parts of the brain affected in dementia.


Nonlinear_association_between_sleep-duration_and_cognitive-function_mental-health_and_brain-structure

 

This study also looked at these non-linear patterns as they were reflected by different age groups. Their results showed that as the participants got older, there was a decrease both in brain volume and cognitive function, with the most significant relationship showing up for participants between the ages of 44 to 59 years. Interestingly the results were a bit different when it came to mental health. The study clearly showed that the association between the participant’s sleep duration and their mental health and cognition gradually decreased as the participants approached 65 and beyond.

The researchers also further strengthened their findings by following up with those people who had non-optimal sleep duration at the beginning of the study. Follow up revealed that over time there was a decrease in these participant’s cognitive function and an increase in psychiatric symptoms.

What This Study Means For Your Cognitive Health

So, all this data may be interesting, but what does it mean in practical terms for your health? Most importantly, is there an optimal number of hours of sleep that you should get to preserve your cognitive function and your emotional health?

The big takeaway from this study is that the regulation of your sleep, in terms of its duration, is vital for optimal brain functioning as well as your mental health and wellbeing. Sleep also seems to be in a pathway that also includes genetics and other brain mechanisms.

 

The Goldilocks Rule

The study identified a consistent sleep pattern of approximately seven hours as being the best for optimal long term health. To paraphrase Goldilocks, “not too little and not too much, but just right.

The researchers further underscore that for those people who have jobs that require them to do shift work and/or travel, this recommendation is particularly important. Keep in mind that too little sleep as well as too much sleep has been shown to be detrimental.

This does not mean you have to sleep exactly seven hours every night. You may do fine on a little less or a little more sleep, but you certainly should not be sleeping several hours less or more than seven.

The other point the study made is around sleep consistency. You don’t want the number of hours you sleep each night to be jumping all over the place every week, such as five hours one night then six the next and eight for the next couple of nights and so forth. Try your best, within reason to keep the number of hours you sleep each night near a consistent number, ideally seven.

Many individuals, as they grow older, experience a change in their sleep patterns. These changes include difficulty falling asleep as well as staying asleep, and a decrease in both the quantity and quality of the sleep they do get. Optimization of sleep is a whole topic in itself, but the most important tips are to stick to a relaxing evening routine, avoid bright light exposure in the evenings, especially the blue light from electronic screens and LED light bulbs, avoid caffeine intake at least six hours before bed, and limit fluid intake after 8pm.

The other very effective thing you can do in the morning, as soon as you get up and before you are exposed to artificial light, is to get outside and get some sunlight on your face for at least five minutes. This natural light exposure will set your master circadian clock for the day and will set you up for a good sleep that night.

 

Of course, fine tuning your sleep is only one part in the whole journey toward optimizing your health. You can do this with a combination of approaches, not only by getting consistent quality sleep, but with exercise, stress control, nutrition and targeted supplementation.

 

References:

 

1. Sean M. Nestor, Raul Rupsingh, Michael Borrie, Matthew Smith, Vittorio Accomazzi, Jennie L. Wells, Jennifer Fogarty, Robert Bartha, the Alzheimer's Disease Neuroimaging Initiative, Ventricular enlargement as a possible measure of Alzheimer's disease progression validated using the Alzheimer's disease neuroimaging initiative database, Brain, Volume 131, Issue 9, September 2008, Pages 2443–2454, https://doi.org/10.1093/brain/awn146.

2. Li, Y, Sahakian, BJ, et al. The brain structure and genetic mechanisms underlying the nonlinear association between sleep duration, cognition, and mental health. Nature Aging; 28 Apr 2022 | DOI:10.1038/s43587-022-00210-2

3. Westwood, A. J. et al. Prolonged sleep duration as a marker of early neurodegeneration predicting incident dementia. Neurology 88, 1172–1179 (2017).

4. Sabia, S. et al. Association of sleep duration in middle and old age with incidence of dementia. Nat. Commun. 12, 2289 (2021).

5. Ma, Y. J. et al. Association between sleep duration and cognitive decline. JAMA Netw. Open 3, e2013573 (2020).

6. Lo, J. C., Loh, K. K., Zheng, H., Sim, S. K. Y. & Chee, M. W. L. Sleep duration and age-related changes in brain structure and cognitive performance. Sleep 37, 1171–1178 (2014).

7. Xu, W. et al. Sleep characteristics and cerebrospinal fluid biomarkers of Alzheimer’s disease pathology in cognitively intact older adults: the CABLE study. Alzheimers Dement. 16, 1146–1152 (2020).

8. Liang, Y., Qu, L. B. & Liu, H. Non-linear associations between sleep duration and the risks of mild cognitive impairment/dementia and cognitive decline: a dose–response meta-analysis of observational studies. Aging Clin. Exp. Res. 31, 309–320 (2019).

40s and 60s Health Academic Performance Active Aging Active Lifestyle Active Living adenosine triphosphate Adoptive cell therapy Aerobic Health Age Prevention Age Reversal Age-Associated Muscle Decline Age-Defying Secrets Age-Defying Strategies Age-Defying Tips Age-related CAR-T failure Age-Related Changes Age-Related Decline Age-Related Diseases Age-Related Myths Age-related Weight Gain Age-specific Nutrition Ageless Beauty Ageless Living Ageless Memory Aging and cancer Aging and Disease Aging and Health Aging and longevity Aging and Nutrition Aging Atlas aging eggs Aging Gracefully Aging Process Aging Research Aging Supplements AI stem cells Alternative Polyadenylation Alzheimer's Alzheimer's Prevention Alzheimer's treatment Alzheimer’s disease AMP-activated protein kinase AMPK anti-aging Anti-Aging Diet Anti-Aging for the Brain Anti-Aging Lifestyle Anti-Aging Research Anti-Aging Science Anti-Aging Strategies Anti-Aging Therapies Anti-Aging Tips Anti-inflammatory diet Anti-Inflammatory Foods Anti-Inflammatory Strategies AntiAging Antioxidant Supplements Antioxidants apoptosis Arterial Stiffness Athletic Training ATP Autophagie autophagy Balanced Diet Balanced Training BCAAs Behavior Modulation Berberine Bioactive Compounds Bioavailability Biological Aging biological clocks Biological Mysteries Biomarkers Biomedical Advances Biomedical engineering Black Pepper Extract blood cell counts Blood Sugar Management blood sugar regulator Blueberries and Grapes Bone Health Brain Boosting Tips Brain Exercises Brain Fitness Brain Function Brain Function Enhancers Brain Health Brain Nutrition Brain Science Brain Supplements Brain Training Brain-Boosting Diet BRCA2 Breakthrough Treatments CaffeineProsAndCons Caloric Restriction Cancer Cancer and Inflammation Cancer Prevention Cancer Research Cancer Therapy Cancer treatment CAR-T therapy CAR-T therapy for older patients CardiacRehabilitation Cardiovascular Health CardiovascularDisease CardiovascularEffects CD38 enzyme Cellular Aging Cellular energy Cellular Growth Cellular Health Cellular health optimization Cellular metabolism Cellular Rejuvenation Cellular Renewal Cellular Senescence Cerebral Blood Flow chAge Chimeric antigen receptor Cholesterol and Cancer Cholesterol Reduction Cholesterol Synthesis Chronic Disease Prevention Chronic Diseases Chronic Inflammation ChronicInflammation ChronicStress chronological age Circadian Rhythm Clinical Trials CoffeeHealth cognition Cognitive Aging Cognitive Enhancement cognitive function Cognitive Health Cognitive Longevity Cognitive Renewal Cognitive Training Cognitive Wellness Continuous Growth coptis chinensis Cork Tree Cortex phellodendri Daily Step Count Dementia Prevention Diabetes Diabetes Management Diabetes Prevention Diabetes Risk Factors Diet and Cancer Diet Tips Dietary Choices Dietary Guidelines Dietary Moderation Benefits Dietary Supplements DietaryResearch Digestive Wellness Digital Learning Disease Prevention DNA methylation DNA Repair DNA Repair and Aging DNA Secrets DNAm Drug Delivery Drug Development Duke-NUS Discoveries eAge Educational Research Emergency Workers Fitness Emotional Wellness Endothelial dysfunction Endurance Training Energy Metabolism epigenetic age epigenetic alterations Epigenetic Clock epigenetische Alter Epigenetische Uhr Ergothioneine Ergothioneine Benefits Evergreen Health Exercise and Aging Exercise and Health Exercise and Immunity Exercise and Inflammation Exercise Physiology Exercise Research Exercise Science Exercise Tips fasting FAXDC2 Enzyme female fertility ferulic acid Fitness and Wellness Fitness in Aging Fitness Recovery Fitness Risks Fitness Tips Focus and Concentration Focus and Recall Focus Enhancement Food Science Functional Foods Functional hyperemia Future of Longevity Future of Medicine gene expression Gene Expression and Longevity Gene Therapy GeneActivity Genetic Aging Genetic Blueprint Genetic Code Genetic Mutations Genetic Research Genexpression genomic instability Genomic Technologies genomics Gerontology Research geroprotection gesundes Altern GLTD Research gluconeogenesis glucose metabolism glycogenolysis Glycolysis Golden Years Golden Years Wellness Goldthread Grape Seed Extract grey hair causes Gut Bacteria Gut Health Gut Microbiome hallmarks of aging Harvard Study Insights Healing Mechanisms Health and Fitness Health and Longevity Health and Wellness Health and Wellness Tips Health Benefits Health Innovation Health Monitoring Health Promotion Health Research Health Risks of Exercise Health Risks of Sitting Health Science Health Supplements HealthAndWellbeing Healthcare Technology Healthspan Extension healthy aging Healthy Aging Tips Healthy Eating Healthy Lifestyle Healthy Living HealthyAging HealthyLifestyle heart health Heart Health in 40s HeartDiseasePrevention HeartHealth Herbal Remedies Hericium Erinaceus Herz Gesundheit high fat ketogenic diet High-Intensity Workouts Holistic Health Holistic Wellness HolisticWellness Hormonal Balance Horvath clock Human longevity Human Trials immune system Immune System and Aging Immune System Health Immunotherapy Improving CAR-T outcomes Inflamm-aging Inflammation Inflammation Insights Inflammation Management Inflammatory Diseases Innovative medical technology Insulin Resistance Insulin/IGF-1 Signaling intercellular communication intermittent fasting keto diet ketogenic diet ketones ketones bodies Kognitive Gesundheit Krebs cycle L-Ergothioneine Life Stages and Wellness LifeExtension Lifelong Clarity Lifelong Learning Lifespan Extension Lifespan Research Lifestyle and Wellness Lifestyle Changes Lifestyle Tips LifestyleChanges Lion's Mane Liposomal NMN Liposomal Technology Liposome Benefits Liposome Manufacturing Liposomes live longer living robots Longevity longevity gene Longevity Research Longevity Secrets Longevity Supplements loss of resilience Love and Longevity matsutake MCI Medical Research Meditation Mediterranean Diet Memory Aids Memory Boosters Memory Consolidation Memory Encoding Memory Enhancement Memory Improvement Memory Mastery Memory Palace Memory Retention Memory Strategies Memory Techniques Memory Tips Memory Training Menschliche Langlebigkeit Mental Agility Mental Fitness mental health Mental Resilience Mental Vitality Mental Wellbeing Mental Wellness Metabolic Changes Metabolic Disorders Metabolic dysfunction metabolic health Metabolic optimization cancer treatment Metabolic Pathways Metabolic Pathways in Cancer Metabolic Syndrome Metabolic Syndrome Management Metabolism in Aging Metabolite Supplements methionine Methylglyoxal Microbiome Research Microcirculation Midlife Health mild cognitive impairment Mind-Body Connection Mind-Gut Connection MindBodyMedicine Mindful Aging Mindful Eating Mindful Organization Mindfulness Mindfulness and Meditation Mitochondrial Health Mitochondrial optimization Mitophagy Mnemonics Moderate vs Vigorous Exercise Modern Aging Solutions Modern Lifestyle Modern Medicine Modern Science Molecular Biology Molecular Mechanisms Molecular medicine mTor activation Multi-Omics Profiling Muscle Endurance Muscle Mass Preservation NAD+ NAD+ (nicotinamide adenine dinucleotide) NAD+ and immune function NAD+ Benefits NAD+ cancer therapy NAD+ supplementation nadh NAMPT Nanotechnology Natural Compounds Natural Elixirs Natural Health Natural Rejuvenation Natural Remedies Natural Supplements Natural Weight Solutions Nature Cancer Neural Nourishment Neurodegeneration Neurodegeneration Insights Neurodegeneration Prevention Neurodegenerative Conditions Neurodegenerative Disease Prevention Neurodegenerative diseases Neurodegenerative Disorders Neuroinflammation Neurological research Neuroplasticity neuroprotection Neurovascular Coupling Neurovascular Unit Nicotinamide adenine dinucleotide nmn NMN (nicotinamide mononucleotide) NMN Supplements NR (nicotinamide riboside) Nutraceuticals Nutriop Longevity Nutriop Longevity Benefits Nutriop Longevity Products Nutriop Longevity Supplements Nutriop Longevity® Resveratrol PLUS Nutriop Supplements Nutriop Wellness NutriopLongevity Nutriop® Life Nutrition Nutrition for Seniors Nutrition Research Nutritional Guidance Nutritional Science Nutritional Strategies Nutritional Supplements Nutritional Support Omega-3 Fatty Acids Oncology Oncology Innovations oocyte quality Optimal Step Count Oral Health Oxford Academic Study Oxidative stress Oxygen Efficiency P16ink4a Parkinson's therapy Personal Transformation Personalized Exercise Plans Personalized Health Strategies Personalized Medicine Personalized Nutrition Pharmaceutical Development Phellodendron Physical Activity Physical Activity and Brain Phytoalexins Piperine Plant Metabolites Plant-based compounds Plant-Based Diet Polygenic Risk Score (PRS) Positive Thinking Premium supplements Preventative Strategies Preventive Health Preventive Healthcare Probiotics Processed Foods Protein aggregation pterostilbene Quercetin Radiant Health Recall Enhancement Reducing Sitting Time Regenerative Medicine Relationships and Health RelaxationTechniques Reproductive Aging Resilience Resilience Techniques Resveratrol rhizoma coptis chinensis rice bran RING-Bait SASP Science Science of Aging Science-backed supplementation Scientific Advancements Scientific Breakthrough Sedentary Behavior Sedentary Lifestyle Self-Improvement Senior Fitness Senior Health Senior Wellness Senior Wellness Strategies Single-Cell RNA Sequencing SIRT1 sirtuins Sleep and Cognition Sleep and Health Sleep and Metabolism sleep cycles sleep duration Sleep Research sleep stages Spermidin spermidine Step Count Benefits Stoffwechselgesundheit Stress and Weight Stress Management StressAndAging StressManagement StressReduction Student Health Supplement Benefits Supplements Swiss cancer research breakthrough T cell exhaustion Targeted Therapies Targeted Therapy Tauopathy Telomeres Timeless Living Timeless Vitality Transcriptomics Tricarboxylic acid cycle Tricholoma matsutake Tumor Suppression Type 2 Diabetes Prevention University of Lausanne research Urolithin A Vibrant Aging Vigorous Exercise Vitality VO2 Max Fitness Walking for Health Weight Loss for Elderly Weight Management Weizenkeimextrakt Wellness Wellness and Vitality Wellness in Retirement Wellness Journey Wellness Strategies Wellness Tips wheat germ extract Whole Foods Whole Grains Wnt Signaling Wnt Signaling Pathway Workout Safety xenobots yoga Youthful Vitality Zelluläre Seneszenz
Back to blog

Leave a comment

Please note, comments need to be approved before they are published.