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Epigenetic Age Acceleration and Its Link to Healthy Longevity in Older Women

Epigenetic Age Acceleration and Its Link to Healthy Longevity in Older Women

By Max Cerquetti kwiecień 07, 2023 | Alzheimer's Alzheimer’s disease anti-aging biological clocks Cellular Senescence chronological age cognition cognitive function Cognitive Health DNA methylation eAge epigenetic age epigenetic alterations Epigenetic Clock epigenetische Alter Epigenetische Uhr gene expression Genexpression genomic instability genomics hallmarks of aging healthy aging heart health Horvath clock Human longevity Kognitive Gesundheit live longer mental health metabolic health Zelluläre Seneszenz

IntroductionAs the world's population ages, understanding the factors that contribute to healthy aging becomes increasingly important. One area of research that has garnered attention is the study of epigenetic age acceleration (EAA). EAA refers to the difference between a person's biological age, as measured by specific changes in their DNA,...

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Ergothioneine: A Promising Biomarker Linking Health-Conscious Food Patterns to Reduced Cardiometabolic Disease Risk and Mortality

Ergothioneine: A Promising Biomarker Linking Health-Conscious Food Patterns to Reduced Cardiometabolic Disease Risk and Mortality

By Max Cerquetti marzec 27, 2023 | blood sugar regulator Cellular Senescence cognition Cognitive Health Diabetes Ergothioneine gene expression hallmarks of aging healthy aging heart health Human longevity Kognitive Gesundheit L-Ergothioneine live longer mental health mild cognitive impairment neuroprotection Zelluläre Seneszenz

This article discusses a population-based prospective study that aimed to identify plasma metabolites associated with a health-conscious food pattern (HCFP) and a lower risk of cardiometabolic morbidity and mortality during a long-term follow-up. The study found that increased levels of the amino acid ergothioneine were strongly and independently associated with both...

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The Role of Ergothioneine in Aging-Related Diseases: A Closer Look at Its Potential Benefits

The Role of Ergothioneine in Aging-Related Diseases: A Closer Look at Its Potential Benefits

By Max Cerquetti marzec 24, 2023 | Alzheimer's Alzheimer’s disease anti-aging blood sugar regulator Cellular Senescence cognition cognitive function Cognitive Health Diabetes Ergothioneine genomic instability genomics gluconeogenesis glucose metabolism healthy aging heart health Human longevity immune system Kognitive Gesundheit L-Ergothioneine Lion's Mane matsutake mental health mild cognitive impairment neuroprotection Zelluläre Seneszenz

IntroductionAging is a complex process that affects various aspects of our health, making us more susceptible to certain diseases and conditions. Researchers have been studying the role of antioxidants and other compounds in combating the negative effects of aging. One such compound, ergothioneine (ERG), has recently gained attention for its...

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Spermidine-Induced Autophagy: Unlocking the Secrets to Geroprotection

Spermidine-Induced Autophagy: Unlocking the Secrets to Geroprotection

By Max Cerquetti marzec 18, 2023 | anti-aging Autophagie autophagy Cellular Senescence fasting gene expression Genexpression genomic instability genomics geroprotection healthy aging Human longevity live longer longevity gene SIRT1 sirtuins Spermidin spermidine wheat germ extract Zelluläre Seneszenz

IntroductionAging is an inevitable part of life, and as we age, our bodies undergo various changes. One such change is the progressive decline in cellular function, leading to a higher risk of age-related diseases. Scientists have been researching ways to promote healthy aging and extend our lifespans, and recent research...

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Unlocking the Potential of NMN: How Animal Research Proves its Ability to Improve Eyesight and Hearing in Age-Related Disease

Unlocking the Potential of NMN: How Animal Research Proves its Ability to Improve Eyesight and Hearing in Age-Related Disease

By Nutriop Longevity styczeń 31, 2023 | anti-aging Cellular Senescence epigenetic age gene expression Genexpression genomic instability hallmarks of aging healthy aging live longer longevity gene loss of resilience NAD+ neuroprotection Nicotinamide adenine dinucleotide nmn Oxidative stress SIRT1 sirtuins

As we age, our bodies begin to deteriorate, leading to a variety of age-related diseases. One of the most common conditions that come with aging is cellular aging, which can lead to a decline in eyesight and hearing. Currently, treatments are available to help slow the progression of these conditions,...

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Unlocking the Potential of NMN: The Key to NAD+

Unlocking the Potential of NMN: The Key to NAD+

By Nutriop Longevity styczeń 19, 2023 | anti-aging apoptosis ATP Autophagie autophagy blood sugar regulator Cellular Senescence Cognitive Health Diabetes DNA methylation epigenetic alterations genomic instability glucose metabolism hallmarks of aging healthy aging heart health Human longevity intercellular communication Kognitive Gesundheit Krebs cycle live longer longevity gene mental health metabolic health NAD+ nadh neuroprotection Nicotinamide adenine dinucleotide nmn Oxidative stress SIRT1 sirtuins Zelluläre Seneszenz

Nicotinamide mononucleotide (NMN) is a molecule that has gained a lot of well-deserved attention in recent years as a potential anti-aging supplement, both in the scientific community as well as among the general public. This is because NMN has been shown to activate another molecule already present in your body,...

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A Different Kind of Magic Mushroom - How Ergothioneine Can Protect Your Brain

A Different Kind of Magic Mushroom - How Ergothioneine Can Protect Your Brain

By Max Cerquetti lipiec 26, 2022 | anti-aging blood sugar regulator Cellular Senescence chronological age cognition cognitive function Cognitive Health Ergothioneine ferulic acid healthy aging heart health Hericium Erinaceus Human longevity immune system L-Ergothioneine Lion's Mane live longer matsutake mental health metabolic health Neurovascular Unit rice bran Tricholoma matsutake

The search for effective compounds that promise to protect the human brain from the ravages of cognitive decline, including impaired decision making, inability to concentrate, memory loss, confusion, and even full blown dementia, has never been more urgent. According to the Centers for Disease Control in Atlanta, there are 16...

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Genetics, Longevity and Cancer - Current Research Uncovers Surprising Findings

Genetics, Longevity and Cancer - Current Research Uncovers Surprising Findings

By Max Cerquetti kwiecień 24, 2022 | Cellular Senescence chronological age Cognitive Health DNA methylation epigenetic age epigenetic alterations gene expression genomic instability

Everyone is familiar with the widely varying sizes, as well as lifespans, of different mammals. A mouse, weighing in at under an ounce, lives a mere 12 to 18 months. Male elephants can weigh up to 13,000 pounds and have an average lifespan of 60 to 70 years. The blue...

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Spermidine And Its Effects On Human Health And Wellbeing

Spermidine And Its Effects On Human Health And Wellbeing

By Max Cerquetti luty 20, 2022 | Autophagie autophagy Cellular Senescence Cognitive Health epigenetic age Epigenetic Clock epigenetische Alter Epigenetische Uhr gene expression Genexpression gesundes Altern healthy aging heart health Herz Gesundheit Human longevity Kognitive Gesundheit Menschliche Langlebigkeit metabolic health Spermidin spermidine Stoffwechselgesundheit Weizenkeimextrakt wheat germ extract Zelluläre Seneszenz

In 1677, Antony Van Leeuwenhoek, a modestly educated Dutchman who was an unassuming textile business owner, peered through the carefully crafted high-power lens of his microscope and made a startling discovery. Endlessly curious, Leeuwenhoek had already made a number of ground-breaking discoveries using his self-crafted lenses, including the existence of...

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AI-Designed ‘Living Robots’ Provide a Potential New Foundation for Regenerative Medicine

AI-Designed ‘Living Robots’ Provide a Potential New Foundation for Regenerative Medicine

By Nutriop Longevity grudzień 26, 2021 | AI stem cells anti-aging Cellular Senescence living robots Regenerative Medicine xenobots

If reproduction is the hallmark of life, then the world’s first ‘living robots’ may have just stepped out of a petri dish in Burlington, Vermont. Admittedly, ‘stepped out’ may be overstating it, (the AI-designed ‘xenobots’ rolled around unceremoniously in the dish instead) however, they did manage to achieve something quite...

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Cellular Senescence And Aging - What You Can Do

Cellular Senescence And Aging - What You Can Do

By Max Cerquetti marzec 04, 2021 | anti-aging apoptosis Cellular Senescence Diabetes NAD+ Nicotinamide adenine dinucleotide nmn Oxidative stress P16ink4a SASP

Many people are somewhat familiar with the word “senescence” and equate the term as being synonymous with aging. After all, the root of the word is “sen-” meaning old and is also the root of the word “senile” which of course means characteristic of old age.But when biologists speak about...

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