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The New Aging Atlas: Cracking the Code of Longevity

The New Aging Atlas: Cracking the Code of Longevity

By Max Cerquetti lipiec 05, 2024 | Aging Atlas Alternative Polyadenylation Anti-Aging Strategies Anti-Aging Therapies Caloric Restriction Future of Longevity gene expression Gene Expression and Longevity Healthspan Extension Insulin/IGF-1 Signaling Longevity Research Molecular Mechanisms Personalized Medicine Reproductive Aging Single-Cell RNA Sequencing Transcriptomics

01: Unlocking the Secrets of Aging The Revolutionary Aging Atlas Unveiling the Atlas Imagine having a detailed map that shows exactly how each cell in your body ages. In 2024, scientists from HHMI's Janelia Research Campus, Baylor College of Medicine, and Creighton University School of Medicine did just that. They...

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Epigenetic Age Acceleration and Its Link to Healthy Longevity in Older Women

Epigenetic Age Acceleration and Its Link to Healthy Longevity in Older Women

By Max Cerquetti kwiecień 07, 2023 | Alzheimer's Alzheimer’s disease anti-aging biological clocks Cellular Senescence chronological age cognition cognitive function Cognitive Health DNA methylation eAge epigenetic age epigenetic alterations Epigenetic Clock epigenetische Alter Epigenetische Uhr gene expression Genexpression genomic instability genomics hallmarks of aging healthy aging heart health Horvath clock Human longevity Kognitive Gesundheit live longer mental health metabolic health Zelluläre Seneszenz

IntroductionAs the world's population ages, understanding the factors that contribute to healthy aging becomes increasingly important. One area of research that has garnered attention is the study of epigenetic age acceleration (EAA). EAA refers to the difference between a person's biological age, as measured by specific changes in their DNA,...

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Ergothioneine: A Promising Biomarker Linking Health-Conscious Food Patterns to Reduced Cardiometabolic Disease Risk and Mortality

Ergothioneine: A Promising Biomarker Linking Health-Conscious Food Patterns to Reduced Cardiometabolic Disease Risk and Mortality

By Max Cerquetti marzec 27, 2023 | blood sugar regulator Cellular Senescence cognition Cognitive Health Diabetes Ergothioneine gene expression hallmarks of aging healthy aging heart health Human longevity Kognitive Gesundheit L-Ergothioneine live longer mental health mild cognitive impairment neuroprotection Zelluläre Seneszenz

This article discusses a population-based prospective study that aimed to identify plasma metabolites associated with a health-conscious food pattern (HCFP) and a lower risk of cardiometabolic morbidity and mortality during a long-term follow-up. The study found that increased levels of the amino acid ergothioneine were strongly and independently associated with both...

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Spermidine-Induced Autophagy: Unlocking the Secrets to Geroprotection

Spermidine-Induced Autophagy: Unlocking the Secrets to Geroprotection

By Max Cerquetti marzec 18, 2023 | anti-aging Autophagie autophagy Cellular Senescence fasting gene expression Genexpression genomic instability genomics geroprotection healthy aging Human longevity live longer longevity gene SIRT1 sirtuins Spermidin spermidine wheat germ extract Zelluläre Seneszenz

IntroductionAging is an inevitable part of life, and as we age, our bodies undergo various changes. One such change is the progressive decline in cellular function, leading to a higher risk of age-related diseases. Scientists have been researching ways to promote healthy aging and extend our lifespans, and recent research...

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Unlocking the Potential of NMN: How Animal Research Proves its Ability to Improve Eyesight and Hearing in Age-Related Disease

Unlocking the Potential of NMN: How Animal Research Proves its Ability to Improve Eyesight and Hearing in Age-Related Disease

By Nutriop Longevity styczeń 31, 2023 | anti-aging Cellular Senescence epigenetic age gene expression Genexpression genomic instability hallmarks of aging healthy aging live longer longevity gene loss of resilience NAD+ neuroprotection Nicotinamide adenine dinucleotide nmn Oxidative stress SIRT1 sirtuins

As we age, our bodies begin to deteriorate, leading to a variety of age-related diseases. One of the most common conditions that come with aging is cellular aging, which can lead to a decline in eyesight and hearing. Currently, treatments are available to help slow the progression of these conditions,...

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The Story Of Ketones And How They Might Be Able To Prevent Alzheimer’s Disease

The Story Of Ketones And How They Might Be Able To Prevent Alzheimer’s Disease

By Max Cerquetti październik 07, 2022 | adenosine triphosphate Alzheimer's Alzheimer’s disease anti-aging ATP blood sugar regulator fasting gene expression gluconeogenesis glucose metabolism glycogenolysis healthy aging high fat ketogenic diet Human longevity intermittent fasting keto diet ketogenic diet ketones ketones bodies live longer MCI mental health mild cognitive impairment NAD+ neuroprotection Tricarboxylic acid cycle

Your brain is a very "expensive" organ to maintain, in terms of its energy needs. This remarkable structure, weighing about 3 pounds in the average adult, is about 60 percent fat, with the rest of its tissues made up of a combination of water, carbohydrates, protein, and salts. Your brain,...

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Genetics, Longevity and Cancer - Current Research Uncovers Surprising Findings

Genetics, Longevity and Cancer - Current Research Uncovers Surprising Findings

By Max Cerquetti kwiecień 24, 2022 | Cellular Senescence chronological age Cognitive Health DNA methylation epigenetic age epigenetic alterations gene expression genomic instability

Everyone is familiar with the widely varying sizes, as well as lifespans, of different mammals. A mouse, weighing in at under an ounce, lives a mere 12 to 18 months. Male elephants can weigh up to 13,000 pounds and have an average lifespan of 60 to 70 years. The blue...

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Spermidine And Its Effects On Human Health And Wellbeing

Spermidine And Its Effects On Human Health And Wellbeing

By Max Cerquetti luty 20, 2022 | Autophagie autophagy Cellular Senescence Cognitive Health epigenetic age Epigenetic Clock epigenetische Alter Epigenetische Uhr gene expression Genexpression gesundes Altern healthy aging heart health Herz Gesundheit Human longevity Kognitive Gesundheit Menschliche Langlebigkeit metabolic health Spermidin spermidine Stoffwechselgesundheit Weizenkeimextrakt wheat germ extract Zelluläre Seneszenz

In 1677, Antony Van Leeuwenhoek, a modestly educated Dutchman who was an unassuming textile business owner, peered through the carefully crafted high-power lens of his microscope and made a startling discovery. Endlessly curious, Leeuwenhoek had already made a number of ground-breaking discoveries using his self-crafted lenses, including the existence of...

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Sleep, Aging, And Your Brain -  What You Must Know

Sleep, Aging, And Your Brain - What You Must Know

By Max Cerquetti sierpień 20, 2021 | anti-aging Circadian Rhythm Cognitive Health gene expression immune system longevity gene Nutriop® Life SIRT1 sirtuins sleep cycles sleep stages

You’ve likely heard the old saying advising people to get their "beauty sleep". Turns out, that similar to many other folk sayings, there is more wisdom in those words than one would imagine. Getting the right amount of sleep is critical, not only for your health but for optimal cognitive...

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